abstract：:The presence of an affiliative conspecific may alleviate an individual's stress response in threatening conditions. However, the mechanisms and neural circuitry underlying the process of social buffering have not yet been elucidated. Using the domestic pig as an animal model, we examined the effect of a 4-h maternal a...

journal_title：Frontiers in behavioral neuroscience

authors： Kanitz E,Hameister T,Tuchscherer A,Tuchscherer M,Puppe B

更新日期：2016-11-29 00:00:00

abstract：:The eye's pupil undergoes dynamic changes in diameter associated with cognitive effort, motor activity and emotional state, and can be used to index brain state across mammalian species. Recent studies in head-fixed mice have linked arousal-related pupil dynamics with global neural activity as well as the activity of ...

journal_title：Frontiers in behavioral neuroscience

authors： Lee CR,Margolis DJ

更新日期：2016-11-01 00:00:00

abstract：:Down syndrome (DS) is an aneuploidy syndrome that is caused by trisomy for human chromosome 21 resulting in a characteristic cognitive and behavioral phenotype, which includes executive functioning and adaptive behavior difficulties possibly due to prefrontal cortex (PFC) deficits. DS also present a high risk for earl...

journal_title：Frontiers in behavioral neuroscience

authors： Del Hoyo L,Xicota L,Langohr K,Sánchez-Benavides G,de Sola S,Cuenca-Royo A,Rodriguez J,Rodríguez-Morató J,Farré M,Dierssen M,de la Torre R,TESDAD Study Group.

更新日期：2016-10-17 00:00:00

abstract：:This study analyzed ethanol intake in male and female Wistar rats exposed to maternal separation (MS) during infancy (postnatal days 1-21, PD1-21) and environmental enrichment (EE) during adolescence (PD 21-42). Previous work revealed that MS enhances ethanol consumption during adulthood. It is still unknown if a simi...

journal_title：Frontiers in behavioral neuroscience

authors： Berardo LR,Fabio MC,Pautassi RM

更新日期：2016-10-13 00:00:00

abstract：:Although previous studies have suggested that depression may be associated with inhibition of evoked pain but facilitation of spontaneous pain, the mechanisms underlying these relationships are unclear. The present study investigated whether the difference between evoked and spontaneous pain on sensory (descending inh...

journal_title：Frontiers in behavioral neuroscience

authors： Wang N,Li SG,Lin XX,Su YL,Qi WJ,Wang JY,Luo F

更新日期：2016-09-28 00:00:00

abstract：:The avoidance response is present in pathological anxiety and interferes with normal daily functions. The aim of this article is to shed light on performance markers of active avoidance (AA) using two different rat strains, Sprague-Dawley (SD) and Wistar. Specifically, good and poor performers were evaluated regarding...

journal_title：Frontiers in behavioral neuroscience

authors： de Oliveira CC,Gouveia FV,de Castro MC,Kuroki MA,Dos Santos LC,Fonoff ET,Teixeira MJ,Otoch JP,Martinez RC

更新日期：2016-08-24 00:00:00

abstract：:Negative social experiences during adolescence increase the risk of psychiatric disorders in adulthood. Using "resident-intruder" stress, the present study aimed to investigate the effects of adolescent social defeat on emotional and cognitive symptoms associated with psychiatric disorders during adulthood and the eff...

journal_title：Frontiers in behavioral neuroscience

authors： Zhang F,Yuan S,Shao F,Wang W

更新日期：2016-07-20 00:00:00

abstract：:During active tactile exploration with their whiskers (vibrissae), rodents can rapidly orient to an object even though there are very few proprioceptors in the whisker muscles. Thus a long-standing question in the study of the vibrissal system is how the rat can localize an object in head-centered coordinates without ...

journal_title：Frontiers in behavioral neuroscience

authors： Yang AE,Hartmann MJ

更新日期：2016-07-19 00:00:00

abstract：:The primary aim of this study was to evaluate and compare the effectiveness of two specific Non-Invasive Brain Stimulation (NIBS) paradigms, the repetitive Transcranial Magnetic Stimulation (rTMS), and transcranial Direct Current Stimulation (tDCS), in the upper limb rehabilitation of patients with stroke. Short and l...

journal_title：Frontiers in behavioral neuroscience

authors： D'Agata F,Peila E,Cicerale A,Caglio MM,Caroppo P,Vighetti S,Piedimonte A,Minuto A,Campagnoli M,Salatino A,Molo MT,Mortara P,Pinessi L,Massazza G

更新日期：2016-06-24 00:00:00

abstract：:Sleep has been related to emotional functioning. However, the extent to which emotional salience is processed during sleep is unknown. To address this concern, we investigated night sleep in healthy adults regarding brain reactivity to the emotionally (happily, fearfully) spoken meaningless syllables dada, along with ...

journal_title：Frontiers in behavioral neuroscience

authors： Chen C,Sung JY,Cheng Y

更新日期：2016-06-14 00:00:00

abstract：:The developing brain is vulnerable to social defeat during the juvenile period. As complements of human studies, animal models of social defeat provide a straightforward approach to investigating the functional and neurobiological consequences of social defeats. Taking advantage of agonist behavior and social defeat i...

journal_title：Frontiers in behavioral neuroscience

authors： Yu WC,Liu CY,Lai WS

更新日期：2016-06-10 00:00:00

abstract：:The last two decades of research provided evidence for a substantial heterogeneity among feeding-related neurons (FRNs) in the hypothalamus. However, it remains unclear how FRNs differ in their firing patterns during food intake. Here, we investigated the relationship between the activity of neurons in mouse hypothala...

journal_title：Frontiers in behavioral neuroscience

authors： Tang Y,Benusiglio D,Grinevich V,Lin L

更新日期：2016-05-18 00:00:00

abstract：:Animals rely on sensory feedback from their environment to guide locomotion. For instance, visually guided animals use patterns of optic flow to control their velocity and to estimate their distance to objects (e.g., Srinivasan et al., 1991, 1996). In this study, we investigated how acoustic information guides locomot...

journal_title：Frontiers in behavioral neuroscience

authors： Warnecke M,Lee WJ,Krishnan A,Moss CF

更新日期：2016-04-25 00:00:00

abstract：:Visual-to-auditory sensory substitution is used to convey visual information through audition, and it was initially created to compensate for blindness; it consists of software converting the visual images captured by a video-camera into the equivalent auditory images, or "soundscapes". Here, it was used by blindfolde...

journal_title：Frontiers in behavioral neuroscience

authors： Pasqualotto A,Esenkaya T

更新日期：2016-04-21 00:00:00

abstract：:Moral decision making involves affective and cognitive functions like emotional empathy, reasoning and cognitive empathy/theory of mind (ToM), which are discussed to be subject to age-related alterations. Additionally, sex differences in moral decision making have been reported. However, age-related changes in moral d...

journal_title：Frontiers in behavioral neuroscience

authors： Rosen JB,Brand M,Kalbe E

更新日期：2016-04-12 00:00:00

abstract：:5-aza-2'-deoxycytidine (5-aza), an inhibitor of DNA methyltransferases (DNMTs), has been implicated in aversive memory and the function of brain region involved in processing emotion. However, little is known about the role of 5-aza in the reconsolidation of opiate withdrawal memory. In the present study, using the mo...

journal_title：Frontiers in behavioral neuroscience

authors： Liu P,Zhang J,Li M,Sui N

更新日期：2016-03-15 00:00:00

abstract：:While several studies have investigated mouse ultrasonic vocalizations (USVs) emitted by isolated pups or by males in mating contexts, studies of behavioral contexts other than mating and vocalization categories other than USVs have been limited. By improving our understanding of the vocalizations emitted by mice acro...

journal_title：Frontiers in behavioral neuroscience

authors： Grimsley JM,Sheth S,Vallabh N,Grimsley CA,Bhattal J,Latsko M,Jasnow A,Wenstrup JJ

更新日期：2016-03-09 00:00:00

abstract：BACKGROUND:Alcohol consumption during pregnancy and lactation induces detrimental consequences, that are not limited to the direct in utero effects of the drug on fetuses, but extend to maternal care. However, the occurrence and severity of alcohol toxicity are related to the drinking pattern and the time of exposure. ...

journal_title：Frontiers in behavioral neuroscience

authors： Brancato A,Plescia F,Lavanco G,Cavallaro A,Cannizzaro C

更新日期：2016-03-03 00:00:00

abstract：:Cognitive rehabilitation in multiple sclerosis (MS) has been reported to induce neuropsychological improvements, but the persistence of these effects has been scarcely investigated over long follow ups. Here, the results of a multicenter randomized clinical trial are reported, in which the efficacy of 15 week domain s...

journal_title：Frontiers in behavioral neuroscience

authors： Mattioli F,Bellomi F,Stampatori C,Provinciali L,Compagnucci L,Uccelli A,Pardini M,Santuccio G,Fregonese G,Pattini M,Allegri B,Clerici R,Lattuada A,Montomoli C,Corso B,Gallo P,Riccardi A,Ghezzi A,Roscio M,Tola MR,C

更新日期：2016-02-23 00:00:00

abstract：:Ecstatic epileptic seizures are a rare but compelling epileptic entity. During the first seconds of these seizures, ecstatic auras provoke feelings of well-being, intense serenity, bliss, and "enhanced self-awareness." They are associated with the impression of time dilation, and can be described as a mystic experienc...

journal_title：Frontiers in behavioral neuroscience

authors： Gschwind M,Picard F

更新日期：2016-02-17 00:00:00

abstract：:How a stimulus impacts spinal cord function depends upon temporal relations. When intermittent noxious stimulation (shock) is applied and the interval between shock pulses is varied (unpredictable), it induces a lasting alteration that inhibits adaptive learning. If the same stimulus is applied in a temporally regular...

journal_title：Frontiers in behavioral neuroscience

authors： Lee KH,Huang YJ,Grau JW

更新日期：2016-02-11 00:00:00

abstract：:Identifying the biological substrates of complex neurobehavioral traits such as alcohol dependency pose a tremendous challenge given the diverse model systems and phenotypic assessments used. To address this problem we have developed a platform for integrated analysis of high-throughput or genome-wide functional genom...

journal_title：Frontiers in behavioral neuroscience

authors： Bubier JA,Wilcox TD,Jay JJ,Langston MA,Baker EJ,Chesler EJ

更新日期：2016-01-21 00:00:00

abstract：:Huntington's Disease (HD) is a progressive neurodegenerative disorder that causes motor, cognitive, and psychiatric symptoms. In these experiments, we tested if operant training at an early age affected adult cognitive deficits in the zQ175 KI Het (zQ175) mouse model of HD. In Experiment 1 we trained zQ175 mice in a f...

journal_title：Frontiers in behavioral neuroscience

authors： Curtin PC,Farrar AM,Oakeshott S,Sutphen J,Berger J,Mazzella M,Cox K,He D,Alosio W,Park LC,Howland D,Brunner D

更新日期：2016-01-11 00:00:00

abstract：:The rat vibrissal system is an important model for the study of somatosensation, but the small size and rapid speed of the vibrissae have precluded measuring precise vibrissal-object contact sequences during behavior. We used a laser light sheet to quantify, with 1 ms resolution, the spatiotemporal structure of whiske...

journal_title：Frontiers in behavioral neuroscience

authors： Hobbs JA,Towal RB,Hartmann MJ

更新日期：2016-01-05 00:00:00

abstract：INTRODUCTION:Conflicting data exist on sensitivity changes of the melanocortin system during diet-induced obesity. We hypothesized that melanocortin sensitivity depends on diet composition, in particular on the fat content rather than the level of obesity. The aim of this study was to determine the influence of diet co...

journal_title：Frontiers in behavioral neuroscience

authors： van den Heuvel JK,Eggels L,van Rozen AJ,Fliers E,Kalsbeek A,Adan RA,la Fleur SE

更新日期：2015-12-24 00:00:00

abstract：:Decision-making is an ethologically adaptive construct that is impaired in multiple psychiatric disorders. Activity within the mesocorticolimbic dopamine system has been traditionally associated with decision-making. The endocannabinoid system through its actions on inhibitory and excitatory synapses modulates dopamin...

journal_title：Frontiers in behavioral neuroscience

authors： Hernandez G,Cheer JF

更新日期：2015-12-17 00:00:00

abstract：:Down syndrome (DS) individuals present increased risk for Alzheimer's disease (AD) neuropathology and AD-type dementia. Here, we investigated the use of green tea extracts containing (-)-epigallocatechin-3-gallate (EGCG), as co-adjuvant to enhance the effects of environmental enrichment (EE) in Ts65Dn mice, a segmenta...

journal_title：Frontiers in behavioral neuroscience

authors： Catuara-Solarz S,Espinosa-Carrasco J,Erb I,Langohr K,Notredame C,Gonzalez JR,Dierssen M

更新日期：2015-12-11 00:00:00

abstract：:Once acquired, a fearful memory can persist for a lifetime. Although learned fear can be extinguished, extinction memories are fragile. The resilience of fear memories to extinction may contribute to the maintenance of disorders of fear and anxiety, including post-traumatic stress disorder (PTSD). As such, considerabl...

journal_title：Frontiers in behavioral neuroscience

authors： Giustino TF,Maren S

更新日期：2015-11-09 00:00:00

abstract：:The locus coeruleus (LC) is the sole source of noradrenergic projections to the cortex and essential for attention-dependent cognitive processes. In this study we used unilateral optogenetic silencing of the LC in an attentional set-shifting task (ASST) to evaluate the influence of the LC on prefrontal cortex-dependen...

journal_title：Frontiers in behavioral neuroscience

authors： Janitzky K,Lippert MT,Engelhorn A,Tegtmeier J,Goldschmidt J,Heinze HJ,Ohl FW

更新日期：2015-11-04 00:00:00

abstract：:Since the discovery of place cells, the hippocampus is thought to be the neural substrate of a cognitive map. The later discovery of head direction cells, grid cells and border cells, as well as of cells with more complex spatial signals, has led to the idea that there is a brain system devoted to providing the animal...

journal_title：Frontiers in behavioral neuroscience

authors： Poucet B,Chaillan F,Truchet B,Save E,Sargolini F,Hok V

更新日期：2015-10-30 00:00:00

abstract：:Humans value rewards less when these are delivered in the future as opposed to immediately, a phenomenon referred to as delay discounting. While delay discounting has been studied during the anticipation of rewards and in the context of intertemporal decision-making, little is known about its neural correlates in the ...

journal_title：Frontiers in behavioral neuroscience

authors： Ludwig VU,Nüsser C,Goschke T,Wittfoth-Schardt D,Wiers CE,Erk S,Schott BH,Walter H

更新日期：2015-10-29 00:00:00

abstract：:Prior studies have shown that intermittent noxious stimulation has divergent effects on spinal cord plasticity depending upon whether it occurs in a regular (fixed time, FT) or irregular (variable time, VT) manner: In spinally transected animals, VT stimulation to the tail or hind leg impaired spinal learning whereas ...

journal_title：Frontiers in behavioral neuroscience

authors： Lee KH,Turtle JD,Huang YJ,Strain MM,Baumbauer KM,Grau JW

更新日期：2015-10-21 00:00:00

abstract：:Discrete populations of brain cells signal differing types of spatial information. These "spatial cells" are largely confined to a closely-connected network of sites. We describe here, for the first time, cells in the anterior claustrum of the freely-moving rat encoding place, boundary and object information. This nov...

journal_title：Frontiers in behavioral neuroscience

authors： Jankowski MM,O'Mara SM

更新日期：2015-10-14 00:00:00

abstract：:Damage involving the anterior thalamic and adjacent rostral thalamic nuclei may result in a severe anterograde amnesia, similar to the amnesia resulting from damage to the hippocampal formation. Little is known, however, about the information represented in these nuclei. To redress this deficit, we recorded units in t...

journal_title：Frontiers in behavioral neuroscience

authors： Jankowski MM,Passecker J,Islam MN,Vann S,Erichsen JT,Aggleton JP,O'Mara SM

更新日期：2015-10-13 00:00:00

abstract：:Prospective memory (PM) refers to the ability to remember to perform intended actions in the future. Although PM deficits are a prominent impairment in schizophrenia, little is still known about the nature of PM in symptomatically remitted patients with schizophrenia. To address this issue, event-related brain potenti...

journal_title：Frontiers in behavioral neuroscience

authors： Chen G,Zhang L,Ding W,Zhou R,Xu P,Lu S,Sun L,Jiang Z,Li H,Li Y,Cui H

更新日期：2015-09-30 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) is a trophic factor regulating cell survival and synaptic plasticity. Recent findings indicate that BDNF could be a potential regulatory factor for cognitive functioning in normal and/or neuropathological conditions. With regard to neurological disorders, recent data suggest th...

journal_title：Frontiers in behavioral neuroscience

authors： Costa A,Peppe A,Carlesimo GA,Zabberoni S,Scalici F,Caltagirone C,Angelucci F

更新日期：2015-09-15 00:00:00

abstract：:To gain further knowledge on the preclinical phase of Alzheimer's disease (AD), we sought to characterize cognitive performance, neuroimaging and plasma-based AD biomarkers in a cohort of non-demented adults with down syndrome (DS). The goal of the down syndrome biomarker Initiative (DSBI) pilot is to test feasibility...

journal_title：Frontiers in behavioral neuroscience

authors： Rafii MS,Wishnek H,Brewer JB,Donohue MC,Ness S,Mobley WC,Aisen PS,Rissman RA

更新日期：2015-09-14 00:00:00

abstract：:The endocannabinoid (eCB) system possesses neuromodulatory functions by influencing the release of various neurotransmitters, including γ-aminobutyric acid (GABA) and glutamate. A functional interaction between eCBs and the serotonergic system has already been suggested. Previously, we showed that cannabinoid type-1 (...

journal_title：Frontiers in behavioral neuroscience

authors： Häring M,Enk V,Aparisi Rey A,Loch S,Ruiz de Azua I,Weber T,Bartsch D,Monory K,Lutz B

更新日期：2015-09-03 00:00:00

abstract：:Early life adversity increases anxiety in adult rodents and primates, and increases the risk for developing post-traumatic disorder (PTSD) in humans. We hypothesized that early adversity impairs the use of learning signals -negative, aversive prediction errors-to reduce fear in uncertainty. To test this hypothesis, we...

journal_title：Frontiers in behavioral neuroscience

authors： Wright KM,DiLeo A,McDannald MA

更新日期：2015-08-27 00:00:00

abstract：:The notion that epigenetics may play an important role in the establishment and maintenance of sex differences in the brain has garnered great enthusiasm but the reality in terms of actual advances has been slow. Two general approaches include the comparison of a particular epigenetic mark in males vs. females and the...

journal_title：Frontiers in behavioral neuroscience

authors： McCarthy MM,Nugent BM

更新日期：2015-08-21 00:00:00